Zhejiang University
High-throughput liquid handling experiments, which demand precision and efficiency, are fundamental to the daily work of Professor F's research team at the College of Biosystems Engineering and Food Science at Zhejiang University (shortened as the College of Bioengineering and Food Science). Achieving both accuracy and efficiency with minimal errors has always been Professor F’s higher standard for scientific experiments. Driven by relentless pursuit of scientific exploration and a spirit of reaching new heights, every team member treats even the most basic liquid handling steps with great meticulousness, leading to continuous progress. However, traditional pipetting methods come with numerous limitations, making it difficult for researchers to be both "efficient and accurate." For example, the basic operation scenario in a poultry molecular detection experiment:
1.Each experiment requires adding more than five special sample reagents (volatile) into a custom 12-well plate.
2.Different reagents have different volumes (e.g., 3μL, 4μL, 5μL, 0.5μL, 0.7μL).
3.Each experiment requires processing a large number of 12-well plates, sometimes exceeding one hundred. Each experiment takes 3-4 days. Such high-intensity, time-consuming unequal micro-liquid experiments inevitably push experimenters to the brink of "inability to concentrate fully and mental breakdown."
Challenges Faced by Professor F's Team Before Using the COEVOS Intelligent Pipetting System
1.Despite being fully equipped with traditional pipettes from a well-known imported brand, repeated volume adjustment was still required (each adjustment took 8 seconds).
2.Single-channel pipetting required at least 2800 repetitions.
3.Due to the special nature of the reagents, differences in experimenters’ physical strength and prolonged operations easily led to splashing into other wells, causing cross-contamination and resulting in the entire plate and reagents being discarded (roughly estimated to have a 15% cross-contamination rate).
4.Due to the volatility of special reagents, it was necessary to repeatedly open the cap at least 1400 times during each experiment to aspirate the solution.
Just the above-mentioned points made the entire experimental process distressing for the operators. Such work also quickly exhausted researchers' rigor and enthusiasm, harming the sustainability and creativity of scientific research.
Unlocking Research Challenges with the COEVOS Digital Key At the beginning of the Year of the Dragon, the team learned that Coevos launched a “talking pipette— the COEVOS Intelligent Digital Pipetting System.” They decided to try it out and immediately found this product to be the “magic tool” they needed for liquid handling. After trial verification, they decisively purchased and equipped it for daily experiments. Let’s hear the “user experiences”:
1.Volume adjustment significantly accelerated: With the intelligent equal volume dispensing function, presetting the needed volume allowed for over four samples to be pipetted with one aspiration, and each volume adjustment took a maximum of 5 seconds (efficiency increased by 38%).
2.Liquid transfer speed increased fourfold: The multi-channel pipette adopted a 4-channel dispensing method, reducing the previous 2800 aspirations to 700 (efficiency increased fourfold).
3.Error rate dropped from 15% to nearly 0: By adjusting the dispensing speed to the X setting, splashing and cross-contamination were eliminated (previously 15%).
4.The number of sample tube openings reduced fourfold, from 1400 times to over 300 times, saving time and greatly reducing reagent evaporation loss.
User Feedback: Students said: "Thanks to the assistance of Coevos’ Intelligent Pipetting System, our experimental process, which previously took 3-4 days, has been quickly shortened to 1-1.5 days." Professor F, the team leader, commented: "It’s surprising that our domestic product now brings us such delightful experiences and real benefits in cost reduction and efficiency improvement. Our team members have greatly increased their interest in scientific experiments, and their enthusiasm for exploring and innovating despite difficulties is rising. Furthermore, all experimental data can be traced, improving the reproducibility of valuable experiments. The team’s atmosphere has become more rigorous yet lively!"
On the path of scientific research, Coevos accompanies you, making your experiments more exciting! The OTA remote upgrade function will allow users to enjoy more convenient and quick operations, more experimental solutions, significantly improving experimental efficiency, making the basic experimental process more elegant, and the results more perfect!
